Characteristics of Poly-L-Lactic Acid (PLLA)

Poly-l-lactic Acid (PLLA) is has been safely used in an array of clinical applications for over 30 years including dissolvable sutures, intrabone implants, and soft-tissue implants. It was first introduced as an agent for "facial filling" of lipotrophic HIV patients in 2004,after having been available in Europe since 1999.

1.In the years since its initial US approval in this difficult-to-treat population, clinical experience has led to development of treatment strategies that minimize the incidence of adverse events observed in the initial clinical trials.

2.Technical advances, coupled with an improved understanding of the contribution of volume loss to facial aging, has led to the emergence of PLLA as a safe and effective treatment for the volume loss that is known to lead to a sagging or deflated appearance,one of the hallmarks of facial aging.

3.Soft-tissue augmentation is an option in facial rejuvenation that has grown considerably in popularity, as it is an efficient means to correct volume loss and is minimally invasive.

4.When assessing patients for whom revolumization with fillers is appropriate, the physiochemical properties of each treatment option should be considered to inform treatment selection.

Edit By:Bella